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5 Best Dog and Cat Antibiotics

September 17, 2025 by Charlie

Top picks at a glance

  1. Dechra Clavacillin Tablets for Dogs & Cats
  2. Amoxi-Tabs (Amoxicillin) Tablets (or Solution) for Dogs and Cats
  3. Neo-Poly-Bac (Generic) Ophthalmic Ointment for Dogs & Cats

Ready to buy now? Shop the best: 

  • Best of the Best: Clavacillin Tablets for Dogs & Cats
  • Best Bang for the Buck: Amoxi-Tabs (Amoxicillin) Tablets for Dogs & Cats
  • Treats Eye Infections: Neo-Poly-Bac (Generic) Ophthalmic Ointment for Dogs

Dogs and cats can acquire numerous types of infections that require treatment with antibiotics. Ear, mouth, skin, upper respiratory, urinary tract, gastrointestinal, and eye infections are some of the most common that usually respond well to these veterinarian-prescribed medications. Some antibiotics target certain infections and types of bacteria, while others are broad-spectrum. These drugs can be administered to the eyes and ears, applied topically, or given orally. The type your vet prescribes for your pet will depend on several factors, including the diagnosis, his age, and size. Keep in mind that you will need to follow the dosing instructions closely for proper treatment, otherwise the infection could worsen or reoccur. Many of these antibiotics require a prescription from your vet in order to place the order.